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Filtered Search Results
Medchemexpress LLC Pralsetinib | 2097132-94-8 | 99.98% | 533.60 | 100 MG
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Pralsetinib (BLU-667) is a potent, selective RET kinase inhibitor. It targets wild-type RET and various mutants (V804L, V804M, M918T) and the CCDC6-RET fusion, with IC50s from 0.3 to 0.4 nM. For research use only, it inhibits NSCLC and thyroid cancer xenograft growth driven by RET mutations and fusions, without inhibiting VEGFR-2. Dose-dependent activity is seen in KIF5B-RET Ba/F3 and V804L Ba/F3 allograft tumors.
- Potent and selective RET inhibitor.
- Targets wild-type RET and specific mutants/fusions.
- Inhibits NSCLC and thyroid cancer xenograft growth.
- For research use only.
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Cayman Chemical Phenylpiracetam 5mg
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A nootropic derivative of the GABAergic agent piracetam that has been evaluated for its efficacy in reducing neurological deficits related to cerebral ischemia, epilepsy, and neurobehavioral disorders; intended for research and forensic purposes only
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Medchemexpress LLC GPR4 antagonist 1 | 1197879-16-5 | 98.9% | 431.62 | 5 MG
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GPR4 antagonist 1 is a GPR4 antagonist, with an IC50 of 189 nM. It is for research use only and not sold to patients.
- GPR4 antagonist with an IC50 of 189 nM.
- Available in various quantities.
- Available in solution or as an oil.
- Shipping at room temperature in the continental US.
- Specific storage instructions are provided for pure form and in solvent.
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Selleck Chemical LLC SB 265610 S9516-25MG
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SB265610 a competitive antagonist at the human CXCR2 receptor can displace [125I]-IL-8 and [125I]-GRO with pIC50 values of 8 41 and 8 47 respectively preventing receptor activation by binding to a region distinct from the agonist binding site
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Selleck Chemical LLC Dipotassium glycyrrhizinate S9222-5MG
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Glycyrrhizinate dipotassium (Neubormitin) is a widely used anti-inflammatory agent isolated from the licorice root
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Selleck Chemical LLC Sinensetin S9227-1MG
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Sinensetin (Pedalitin Permethyl ether) a natural polymethoxylated flavone has potent antiangiogenesis activity
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Selleck Chemical LLC Securinine S9249-1MG
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Securinine a major natural alkaloid product from the root of the plant Securinega suffruticosa acts as a -amino butyric acid (GABA) receptor antagonist
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369781 DBCO-PEG3-NHS ESTER 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369782 GSK-J4 HYDROCHLORID 10MM 1ML
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Medchemexpress LLC Z-Phe-Arg-pNA | 117761-01-0 | 99.9% | 575.62 | 5 MG
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Z-Phe-Arg-pNA is a substrate of Cathepsin L.
- Substrate of Cathepsin L
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Cayman Chemical 5-ndrostn-3a 17-dIol 5mg
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A metabolite of testosterone
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Medchemexpress LLC 4-Aminobenzyl alcohol | 623-04-1 | 123.15 | 25 G
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4-Aminobenzyl alcohol is a self-eliminating linker used to synthesize the fluorescent probe MB-Van1. This probe targets Vanin-1 and allows for real-time imaging of its activity in various inflammatory mouse models, including rheumatoid arthritis, drug-induced liver injury, and non-steroidal anti-inflammatory drug enteropathy. The probe undergoes an efficient self-elimination reaction after activation by the Vanin-1 enzyme, leading to significant signal amplification.
- Can be used to synthesize fluorescent probes
- Targets Vanin-1
- Allows real-time imaging of Vanin-1's activity
- Suitable for various inflammatory mouse models
- Undergoes efficient self-elimination
- Provides significant signal amplification
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Medchemexpress LLC 4-Bromopicolinic acid | 30766-03-1 | 202.01 | 25 G
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4-Bromopicolinic acid is a biochemical reagent suitable for life science-related research, serving as a biological material or organic compound. It is also a useful synthetic intermediate for agrochemical, pharmaceutical, and dyestuff fields.
- Biochemical reagent for life science research
- Can be used as a biological material or organic compound
- Useful synthetic intermediate for various industries
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![Medchemexpress LLC (3S)-3-[[(2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]pyrrolidine-2-car... | 1230628-71-3 | MFCD28386195 | 98.4% | 477.94 g/mol | C22H28ClN5O5 | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235355.png-250.jpg)
Medchemexpress LLC (3S)-3-[[(2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]pyrrolidine-2-car... | 1230628-71-3 | MFCD28386195 | 98.4% | 477.94 g/mol | C22H28ClN5O5 | 50MG
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ML132 (NCGC-00183434) is a selective caspase-1 inhibitor used as a molecular probe in research on inflammation and cancer. It exhibits an IC50 of approximately 34.9 nM and is provided as a high-purity small-molecule solid for laboratory research applications.
- Selective caspase-1 inhibitor, IC50 ≈ 34.9 nM.
- High reported purity (~98.4%).
- Molecular formula C22H28ClN5O5; molecular weight 477.94 g/mol.
- Stable small molecule suitable as a research probe.
- Used in anti-inflammatory and anticancer pathway studies.
- Store at -80°C, protect from light, under inert atmosphere.
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Apexbio Technology LLC Reserpine,1gCAS# 50-55-5
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Extracted from Rauvolfia plants;Suitability:Chloroform,dichloromethane,glacial acetic acid;Store the product in sealed,cool and dry condition. Other sizes are also available. Please inqury us for quote.
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